Aqueous 2-methoxyethanol Reaction media: Synthesis of some 4,5-dihydro-pyrazole-1-carbaldehyde derivative

Sainath B Zangade

Sainath B Zangade Department of Chemistry, Madhavrao Patil College, Palam, Dist. Parbhani (M S) India.

Keywords: Aqueous 2-methoxyethanol, N-formyl-2-pyrazoline, I, I- unsaturated ketone, hydrazine hydrate.

Abstract

A novel N-formyl-2-pyrazoline derivative was synthesized by reaction of an α,β- unsaturated ketone with hydrazine hydrate and formic acid in aqueous 2-methoxyethanol reaction media. The Clean reaction conditions, simple workup procedure and short reaction time giving high yields of product are notable advantages of method. The structure of the title compound was established by IR, ¹H NMR, ¹³C NMR and analytical data.

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