Phytochemical Investigation of the Roots of Jatropha Integerrima Jacq

Abstract

Jatropha   integerrima Jacq.  (Euphorbiaceae),  is  grown in many tropical and subtropical countries   and used  to treat eczema, herpes, ringworm, rheumatism, pruritus, scabies, toothaches, tumors and warts.  Its latex is toxic. A methanolic extract of  the  roots  was  chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol successively in order of increasing  polarity to isolate  n-pentadecanyl oleate (1), α-D-glucopyranosyl-(2→1')-O-α-D-glucopyranoside (α-D-diglucoside, 2),  n-hexanoyl-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranoside (n-caproyl O-α-D-pentaglucoside, 3), n-hexanoyl-O-β-D-glucopyranosyl-(2a→1b)-O-β-D-glucopyranosyl-(2b→1c)-O-β-D-glucopyranosyl-(2c→1d)-O-β-D-glucopyranosyl-(2d→1e)-O-β-D-glucopyranosyl-(2e→1f)-O-β-D-glucopyranoside  (n-caproyl O-β-D-hexaglucoside, 4),  α -D-glucopyranosyl-(2→1a)-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranoside (α-D-hexaglucoside 5) and α -D-glucopyranosyl-(2→1a)-O- α -D-glucopyranosyl-(2a→1b)-O- α -D-glucopyranosyl-(2b→1c)-O- α -D-glucopyranosyl-(2c→1d)-O- α -D-glucopyranosyl-(2d→1e)-O- α -D-glucopyranosyl-(2e→1f)-O- α -D-glucopyranoside (α-D-heptaglucoside, 6) . The structures of these compounds have been established on the basis of spectral data analysis and chemical means.